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53 Kawahara-cho, Shogoin,
Sakyo-ku,Kyoto 606-8507,
JAPAN
Department of Biological Repair,
Field of Clinical Application,
Institute for Frontier Medical Sciences,
Kyoto University
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We are developing a cell replacement therapy for the neurological disorders by using stem cells, especially embryonic stem cells (ES cells). The main target is Parkinson's disease, and our research focuses on induction of dopaminergic neurons from ES cells and transplantation of the cells into the brain to improve neurological symptoms.
We have revealed the optimal differentiational stage for an efficient survival of the grafted dopaminergic neurons, and also a method to prevent tumor formation. In addition, we have demonstrated that transplantation of monkey ES cell-derived neurons improved the Parkinsonian symptoms of the monkey models. As a next step, we hope to examine the long-term efficacy and safety of human ES cell transplantation in primate models. |
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| Professor |
Jun Takahashi
MD, PhD
Neurosurgeon
CV |
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| Junior Assosiate Professor |
Daisuke Doi
MD, PhD
Neurosurgeon
CV (PDF) |
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| Assistant Professor |
Tetsuhiro Kikuchi
MD, PhD
Neurosurgeon
CV (PDF) |
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Fabian Raudzus
PhD |
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| Researcher |
Asuka Morizane
MD, PhD
Neurosurgeon
CV (PDF) |
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Emi Yamasaki
PhD |
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Bumpei Samata |
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| Technical Staff |
Kei Kubota |
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Tomoka Ashida |
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Rika Takaichi |
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Yuko Konoshima |
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Kaori Fukushima |
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Seiya Baba |
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Aya Iwata |
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Mami Okamoto |
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Misaki Fujii |
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| Research Student |
Ryosuke Tsuchimochi
MD
Neurosurgeon |
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| Graduate student |
Hiromasa Adachi
MD
Neurosurgeon |
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Hokuto Yamashita
MD
Neurosurgeon |
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Naoko Kubo |
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| Special Research Student |
Keitaro Yamagami
MD
Neurosurgeon |
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| Visiting Researcher |
Yasuharu Otsubo |
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Kenji Yoshida |
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Satoe Hiramatsu |
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Hideaki Takahashi |
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Yusuke Sugao |
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Megumi Ikeda |
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Yusaku Kodaka |
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| Secretary |
Natsuko Hada |
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Yuki Kawamoto |
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 Institute for Frontier Medical Sciences, KyotoUniversity
Department of Neurosurgery, Graduate School of Medicine, KyotoUniversity
Kyoto University
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